Based on our computer projections, the No. 5 Notre Dame Fighting Irish will defeat the USC Trojans when the two teams match up at Los Angeles Memorial Coliseum on Saturday, Nov. 30, which kicks off at 3:30 p.m. ET. For our predictions on the spead, point total, and final score, see the rest of the article below.

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Notre Dame vs. USC Predictions and Picks

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Notre Dame Betting Info (2024)

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• Based on this contest’s moneyline, the Fighting Irish have an implied win probability of 74.0%.
• The Fighting Irish have eight wins in 11 games against the spread this season.
• In games this season when favored by 7.5 points or more, Notre Dame are 6-2-1 against the spread.
• The Fighting Irish have played 11 games this season and six of them have gone over the total.
• The over/under in this game is 52.5 points, 5.6 higher than the average total in Notre Dame games this season.

USC Betting Info (2024)

• The implied probability of a win by the Trojans based on the moneyline is 30.3%.
• So far this season, the Trojans have put together a 7-4-0 record against the spread.
• Four of the Trojans’ 11 games with a set total have hit the over (36.4%).
• The average over/under for USC games this season is 1.5 more points than the point total of 52.5 in this outing.

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Fighting Irish vs. Trojans 2024 Scoring Averages

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