Our computer model predicts a win for the Detroit Lions when they meet the Indianapolis Colts at Lucas Oil Stadium on Sunday, Nov. 24 at 1 p.m. ET — for more information regarding the spread, over/under and final score, see below.

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On the offensive side of the ball, the Lions have been a top-five unit, ranking third-best in the NFL by compiling 394.7 yards per game. They rank 13th on defense (327.5 yards allowed per game). The Colts rank 19th in the NFL with 21.5 points per game on offense, and they rank 19th with 22.7 points ceded per game on defense.

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Lions vs. Colts Predictions and Picks

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Lions Betting Info

• The Lions have an implied moneyline win probability of 80.0% in this contest.
• Detroit has put together an 8-2-0 ATS record so far this year.
• The Lions have covered the spread twice when favored by 7.5 points or more this season (in three opportunities).
• So far this season, five of Detroit’s 10 games have hit the over.
• The over/under in this game is 50.5 points, 0.8 higher than the average total in Lions games this season.

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Colts Betting Info

• The bookmakers’ moneyline implies a 24.4% chance of a victory for the Colts.
• Indianapolis has covered eight times in 11 matchups with a spread this season.
• So far this year, five of Indianapolis’ 11 games with a set number have gone over the point total.
• Games involving the Colts this year have averaged 44.3 points per game, a 6.2-point differential when compared to the over/under for this contest.

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Lions vs. Colts 2024 Scoring Insights

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