According to our computer model, the Detroit Lions will defeat the Buffalo Bills when they square off at Ford Field on Sunday, Dec. 15 (at 4:25 p.m. ET). We have more projections, regarding the point spread, total and final score, available below.

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The Lions sport the 10th-ranked defense this year (318.6 yards allowed per game), and they’ve been more effective on the other side of the ball, ranking second-best with 394.8 yards per game. The Bills rank 10th with 355.0 total yards per contest on offense, and they rank 14th with 332.0 total yards given up per contest on defense.

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Lions vs. Bills Predictions and Picks

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Lions Betting Info

• The implied moneyline probability for this matchup gives the Lions a 59.2% chance to win.
• Detroit has put together a 9-4-0 record against the spread this season.
• The Lions have been favored by 2.5 points or more 12 times this season, and covered the spread in eight of those games.
• A total of six out of 13 Detroit games this season have hit the over.
• The over/under for this game is 54.5 points, 4.7 more than the average point total for Lions games this season (playoffs included).

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Bills Betting Info

• The Bills have a 45.5% chance to win this game based on the implied probability of the moneyline.
• Buffalo is 8-5-0 ATS this season.
• The Bills have covered the spread once this year (1-1 ATS) when playing as at least 2.5-point underdogs.
• Buffalo and its opponent have combined to hit the over nine out of 13 times this year.
• The over/under for this game is 8.4 points higher than the average scoring total for Bills games (playoffs included) of 46.1.

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Lions vs. Bills 2024 Scoring Insights

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