The No. 16 Notre Dame Fighting Irish (3-1) play the No. 15 Louisville Cardinals (3-0) on Saturday, September 28, 2024 at Notre Dame Stadium. The Fighting Irish are listed as favorites in this one, with the spread sitting at 6.5 points. The over/under in this outing is 45 points.

In this article, you will check out the spread and odds across multiple sportsbooks for the Notre Dame vs. Louisville matchup.

BetMGM is one of the most trusted Sportsbooks in the nation. Start with as little as $1 and place your bets today.

Notre Dame vs. Louisville Game Info

• Date: Saturday, September 28, 2024
• Time: 3:30 p.m. ET
• TV Channel: Peacock
• City: South Bend, Indiana
• Venue: Notre Dame Stadium

Stop missing games and start streaming college football right now on Fubo.

Notre Dame vs. Louisville Odds, Spread, Over/Under

Check out the odds, spread and over/under for this matchup at individual sportsbooks.

Make smart decisions. Use those stats when making your college football picks and place your bet on BetMGM.

Notre Dame vs. Louisville Betting Trends

• Notre Dame has a record of 2-2-0 against the spread this season.
• The Fighting Irish have covered the spread once when favored by 6.5 points or more this season (in three opportunities).
• Louisville has covered twice in two games with a spread this year.

Not all offers available in all states, please visit your sportsbook for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.