The No. 16 Notre Dame Fighting Irish (3-1) will clash with the No. 15 Louisville Cardinals (3-0) at Notre Dame Stadium in South Bend, Indiana. Keep scrolling for a glimpse at the odds and best bets for this game.

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When and Where is Notre Dame vs. Louisville?

• Date: Saturday, September 28, 2024
• Time: 3:30 p.m. ET
• TV Channel: Peacock
• City: South Bend, Indiana
• Venue: Notre Dame Stadium

Notre Dame vs. Louisville Prediction & Moneyline Pick

• Prediction: Notre Dame 28, Louisville 22
• Notre Dame is -241 on the moneyline, and Louisville is +196.
• Notre Dame is 2-1 in games they were listed as the moneyline favorite (winning 66.7% of those games).
• The Fighting Irish are 2-1 (winning 66.7% of their games) when they have played as a moneyline favorite of -241 or shorter.
• This is the first time Louisville will play as an underdog this season.
• The Cardinals have not entered a game this season with longer moneyline odds than +196.
• Based on this contest’s moneyline, the Fighting Irish have an implied win probability of 70.7%.

Make your moneyline wager right now at BetMGM.

Against the Spread Pick

• Pick ATS:

  Louisville (+6.5)
  

• Notre Dame has two wins versus the spread in four games this year.
• This season, the Fighting Irish have just one against the spread win in three games as a favorite of 6.5 points or more.
• Thus far in 2024 Louisville has two wins against the spread.

You can place your bet against the spread at BetMGM.

Best Over/Under Pick

• Pick OU: Over (45)
• Notre Dame and its opponents have combined to exceed Saturday’s total of 45 points once this season.
• Together, the two teams combine for 80.1 points per game, 35.1 points more than the point total of 45 for this game.

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Key Stats Splits

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