Our best bet on the Week 2 FBS slate, in terms of the point spreads, is Troy (+18.5) — see below for more tips (including parlay opportunities) for both spreads and over/unders.

Get insights and computer predictions for that game and more in this article.

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College Football Computer Picks – Best Spread Bets

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Pick: Troy +18.5 vs. Memphis

• Matchup: Troy Trojans at Memphis Tigers
• Projected Winner & Margin: Troy by 3.8 points
• Time: 12:00 PM ET
• Date: September 7
• TV Channel: ESPNU
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Washington -24.5 vs. Eastern Michigan

• Matchup: Eastern Michigan Eagles at Washington Huskies
• Projected Winner & Margin: Washington by 46.3 points
• Time: 3:30 PM ET
• Date: September 7
• TV Channel: BTN

Pick: Michigan +7.5 vs. Texas

• Matchup: Texas Longhorns at Michigan Wolverines
• Projected Winner & Margin: Michigan by 7 points
• Time: 12:00 PM ET
• Date: September 7
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Old Dominion +2.5 vs. East Carolina

• Matchup: East Carolina Pirates at Old Dominion Monarchs
• Projected Winner & Margin: Old Dominion by 11.7 points
• Time: 6:00 PM ET
• Date: September 7
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

Pick: New Mexico State +21.5 vs. Liberty

• Matchup: Liberty Flames at New Mexico State Aggies
• Projected Winner & Margin: Liberty by 8.4 points
• Time: 10:15 PM ET
• Date: September 7
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Use these spread picks at BetMGM today!

College Football Computer Picks – Best Total Bets

Over 57.5 – Georgia Southern vs. Nevada

• Matchup: Georgia Southern Eagles at Nevada Wolf Pack
• Projected Total: 77.3 points
• Time: 7:00 PM ET
• Date: September 7
• TV Channel: truTV

Over 56.5 – South Alabama vs. Ohio

• Matchup: South Alabama Jaguars at Ohio Bobcats
• Projected Total: 75 points
• Time: 6:00 PM ET
• Date: September 7
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

Under 62.5 – Pittsburgh vs. Cincinnati

• Matchup: Pittsburgh Panthers at Cincinnati Bearcats
• Projected Total: 49.5 points
• Time: 12:00 PM ET
• Date: September 7
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Under 61.5 – Tennessee vs. North Carolina State

• Matchup: Tennessee Volunteers at North Carolina State Wolfpack
• Projected Total: 49.7 points
• Time: 7:30 PM ET
• Date: September 7
• TV Channel: ABC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Under 59.5 – Mississippi State vs. Arizona State

• Matchup: Mississippi State Bulldogs at Arizona State Sun Devils
• Projected Total: 48.9 points
• Time: 10:30 PM ET
• Date: September 7
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Take advantage of our picks and place your bet at BetMGM today!

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